Welcome aboard!
The general rule is to drag any lens away from its design space as little as possible.
If you're extending the lens just a little, then the best bet is to turn the ring to its own closest focus, then add minimal extension behind it.
If you're adding lots of extension, taking the lens beyond 1:1, then probably it's better to reverse the lens and set the focus ring to whatever best matches the distance between lens and sensor.
The other general rule is that there are always exceptions. For critical work, be sure to run a real-world test.
--Rik